Function and Biology Details
Reaction catalysed:
2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H(2)O = ribonucleoside diphosphate + thioredoxin
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Ribonucleoside-diphosphate reductase small (preferred)
PDBe Complex ID:
PDB-CPX-140827 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonucleoside-diphosphate reductase small chain 1
Molecule details ›
Chain: A
Length: 419 amino acids
Theoretical weight: 48.38 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Ribonucleotide reductase, small chain
Structure domains: Ribonucleotide Reductase, subunit A
Length: 419 amino acids
Theoretical weight: 48.38 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P09938 (Residues: 1-399; Coverage: 100%)
Sequence domains: Ribonucleotide reductase, small chain
Structure domains: Ribonucleotide Reductase, subunit A
Ribonucleoside-diphosphate reductase small chain 2
Molecule details ›
Chain: B
Length: 345 amino acids
Theoretical weight: 40.1 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Ribonucleotide reductase, small chain
Structure domains: Ribonucleotide Reductase, subunit A
Length: 345 amino acids
Theoretical weight: 40.1 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P49723 (Residues: 1-345; Coverage: 100%)
Sequence domains: Ribonucleotide reductase, small chain
Structure domains: Ribonucleotide Reductase, subunit A
