› 1pvl

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukocidin/Hemolysin toxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 301 amino acids
Theoretical weight: 34.49 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: Q5FBD2 (Residues: 25-325; Coverage: 100%)
Gene names: LukPV-F, NCTC6133_01921, hlgB_1, lukF- PV, lukF-PV, lukPV-F, lukPVF
Sequence domains: Leukocidin/Hemolysin toxin family
Structure domains: Leukocidin/porin MspA

Ligands and Environments

1 bound ligand:
Ligand MES 2 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X31
Spacegroup: P212121
Unit cell:
a: 50.74Å b: 72.38Å c: 98.93Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.201 0.243

Quick links

Citations

14 review citations

Pore-forming protein toxins: from structure to function.
Parker et al. (2005)
13 more

18 mentions without citation

Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance.
Yamamoto et al. (2010)
17 more