› 1erj

X-ray diffraction
2.3Å resolution

CRYSTAL STRUCTURE OF THE C-TERMINAL WD40 DOMAIN OF TUP1

Released:
DOI: 10.2210/pdb1erj/pdb
PDB entry 1erj coloured by chain, front view.
PDB entry 1erj coloured by chain, side view.
PDB entry 1erj coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast.
Sprague ER, Redd MJ, Johnson AD, Wolberger C
EMBO J 19 3016-27 (2000)
PMID: 10856245

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147785 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General transcriptional corepressor TUP1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 393 amino acids
Theoretical weight: 43.31 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P16649 (Residues: 281-388, 432-713; Coverage: 55%)
Gene names: AAR1, AER2, AMM1, CYC9, FLK1, SFL2, TUP1, UMR7, YCR084C, YCR84C
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P31
Unit cell:
a: 119.28Å b: 119.28Å c: 77.07Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.228 0.266
Expression system: Escherichia coli

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Citations

9 review citations

Higher-order structure of chromatin and chromosomes.
Woodcock et al. (2001)
8 more

14 mentions without citation

The substrate specificity of eukaryotic cytosolic chaperonin CCT.
Willison KR. (2018)
13 more