› 1g5v

Solution NMR

SOLUTION STRUCTURE OF THE TUDOR DOMAIN OF THE HUMAN SMN PROTEIN

Released:
DOI: 10.2210/pdb1g5v/pdb
PDB entry 1g5v coloured by chain, ensemble of 10 models, front view.
PDB entry 1g5v coloured by chain, ensemble of 10 models, side view.
PDB entry 1g5v coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
SMN tudor domain structure and its interaction with the Sm proteins.
Selenko P, Sprangers R, Stier G, Bühler D, Fischer U, Sattler M
Nat Struct Biol 8 27-31 (2001)
PMID: 11135666

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172535 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Survival motor neuron protein Chain: A
Molecule details ›
Chain: A
Length: 88 amino acids
Theoretical weight: 9.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16637 (Residues: 82-169; Coverage: 30%)
Gene names: SMN, SMN1, SMN2, SMNC, SMNT
Sequence domains: Survival motor neuron protein (SMN), Tudor domain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: mixed torsion and Cartesian angle dynamics simulated annealing protocol
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

57 review citations

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Taverna et al. (2007)
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10 mentions without citation

The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Qiu et al. (2002)
9 more