› 1koz

Solution NMR

SOLUTION STRUCTURE OF OMEGA-GRAMMOTOXIN SIA

Released:
DOI: 10.2210/pdb1koz/pdb
PDB entry 1koz coloured by chain, ensemble of 20 models, front view.
PDB entry 1koz coloured by chain, ensemble of 20 models, side view.
PDB entry 1koz coloured by chain, ensemble of 20 models, top view.
Source organism: Grammostola rosea
Primary publication:
Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel.
Takeuchi K, Park E, Lee C, Kim J, Takahashi H, Swartz K, Shimada I
J Mol Biol 321 517-26 (2002)
PMID: 12162963

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158050 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Omega-theraphotoxin-Gr1a Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 4.12 KDa
Source organism: Grammostola rosea
Expression system: Not provided
UniProt:
  • Canonical: P60590 (Residues: 50-85; Coverage: 57%)
Sequence domains: Ion channel inhibitory toxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

9 review citations

Tarantulas: eight-legged pharmacists and combinatorial chemists.
Escoubas et al. (2004)
8 more

2 mentions without citation

Molecular surface of tarantula toxins interacting with voltage sensors in K(v) channels.
Wang et al. (2004)
1 more