Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Cyclin E1-CDK2 complex (preferred)
PDBe Complex ID:
PDB-CPX-150301 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cyclin-dependent kinase 2
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 34.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 298 amino acids
Theoretical weight: 34.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P24941 (Residues: 1-297; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
G1/S-specific cyclin-E1
Molecule details ›
Chain: B
Length: 283 amino acids
Theoretical weight: 32.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Cyclin-like
Length: 283 amino acids
Theoretical weight: 32.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P24864 (Residues: 96-378; Coverage: 69%)
Sequence domains:
Structure domains: Cyclin-like
