› 4nn2

X-ray diffraction
1.47Å resolution

Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6

Released:
DOI: 10.2210/pdb4nn2/pdb
PDB entry 4nn2 coloured by chain, front view.
PDB entry 4nn2 coloured by chain, side view.
PDB entry 4nn2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal Structure of the second extended PHD domain of human PHF6 protein
Liu Z, Li F, Zhang J, Mei Y, Wu J, Shi Y
J. Biol. Chem. (2014)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184890 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PHD finger protein 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 129 amino acids
Theoretical weight: 14.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IWS0 (Residues: 208-333; Coverage: 35%)
Gene names: CENP-31, KIAA1823, PHF6
Sequence domains: PHD-like zinc-binding domain
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

2 bound ligands:
Ligand ZN 6 x ZN
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P321
Unit cell:
a: 102.78Å b: 102.78Å c: 51.25Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.159 0.159 0.176
Expression system: Escherichia coli

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