Structure of human Asc1/CD98hc heteromeric amino acid transporter
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8qey
Q-score: 0.365
Rullo-Tubau J, Martinez-Molledo M, Bartoccioni P, Puch-Giner I, Arias A, Saen-Oon S, Stephan-Otto Attolini C, Artuch R, Diaz L, Guallar V, Errasti-Murugarren E, Palacin M, Llorca O
Nat Commun (2024) 15 pp. 2986-2986 [ Pubmed: 38582862 DOI: doi:10.1038/s41467-024-47385-3 ]
- 4f2 cell-surface antigen heavy chain (68 kDa, Protein from Homo sapiens)
- Asc-type amino acid transporter 1 (56 kDa, Protein from Homo sapiens)
- Asc1/cd98hc (Complex from Homo sapiens)
- Digitonin (1 kDa, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin.
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 8rtt
Q-score: 0.444
Oosterheert W, Boiero Sanders M, Funk J, Prumbaum D, Raunser S, Bieling P
To Be Published
- Dimeric fh2 domain of s. pombe cdc12 (Complex from Schizosaccharomyces pombe)
- Phalloidin (808 Da, Protein from Amanita phalloides)
- Complex of the dimeric fh2 domain of s. pombe cdc12 bound to the barbed end of phalloidin stabilized f-actin. (Complex)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Cell division control protein 12 (48 kDa, Protein from Schizosaccharomyces pombe)
- Phalloidin. (Complex from Amanita phalloides)
- Actin, cytoplasmic 1, n-terminally processed (41 kDa, Protein from Homo sapiens)
- Actin filament (Complex from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
Resolution: 6.25 Å
EM Method: Single-particle
Fitted PDBs: 8rty
Q-score: 0.169
Oosterheert W, Boiero Sanders M, Funk J, Prumbaum D, Raunser S, Bieling P
Science (2024) 384 pp. eadn9560-eadn9560 [ Pubmed: 38603491 DOI: doi:10.1126/science.adn9560 ]
- Actin-formin-profilin ring complex: the phalloidin-stabilized f-actin barbed end bound by dimeric-cdc12 and profilin-s71m. (Complex)
- Profilin-1-s29c/s71m (Complex from Homo sapiens)
- Phalloidin (Complex from Amanita phalloides)
- Magnesium ion (24 Da, Ligand)
- Dimeric fh1fh2 domain of s. pombe cdc12 (Complex from Schizosaccharomyces pombe)
- Actin, cytoplasmic 1, n-terminally processed (41 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Profilin-1 (15 kDa, Protein from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Actin filament (Complex from Homo sapiens)
- Methylated-dna--protein-cysteine methyltransferase,cell division control protein 12 (77 kDa, Protein from Schizosaccharomyces pombe)
- Phalloidin (amanita phalloides) (808 Da, Protein from Amanita phalloides)
Structure of the F-actin barbed end bound by formin mDia1
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 8ru2
Q-score: 0.362
Oosterheert W, Boiero Sanders M, Funk J, Prumbaum D, Raunser S, Bieling P
Science (2024) 384 pp. eadn9560-eadn9560 [ Pubmed: 38603491 DOI: doi:10.1126/science.adn9560 ]
- Mouse mdia1 (fh1fh2c domain) (Complex from Mus musculus)
- Magnesium ion (24 Da, Ligand)
- Actin, cytoplasmic 1, n-terminally processed (41 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Mdia1-bound f-actin barbed end. (Complex)
- Actin filament (Complex from Homo sapiens)
- Methylated-dna--protein-cysteine methyltransferase,protein diaphanous homolog 1 (86 kDa, Protein from Mus musculus)
Lysophosphatidylserine receptor GPR34-Gi complex
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8iz4
Q-score: 0.52
Gong W, Liu G, Li X, Wang Y, Zhang X
To Be Published
- Cholesterol (386 Da, Ligand)
- [(2~{r})-2-oxidanyl-3-phosphonooxy-propyl] octadecanoate (438 Da, Ligand)
- Antibody fragment scfv16 (27 kDa, Protein from synthetic construct)
- Serine (105 Da, Ligand)
- Lysops-gpr34-gi-scfv16 complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 34 (64 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
Cryo-EM structure of Lys05 bound GPR30-Gq complex structure
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xof
Q-score: 0.551
To Be Published
- Nanobody35 (Complex from Lama glama)
- Gpr30-gq (Complex from Homo sapiens)
- G-protein coupled estrogen receptor 1 (42 kDa, Protein from Homo sapiens)
- Lys01 (440 Da, Ligand)
- Nanobody35 (15 kDa, Protein from Lama glama)
- Gpr30-gq complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- G protein subunit q (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of apo-GPR30-Gq complex structure
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8xog
Q-score: 0.462
To Be Published
- Gpr30-gq (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha-q (41 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from synthetic construct)
- G-protein coupled estrogen receptor 1 (42 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from synthetic construct)
- Water (18 Da, Ligand)
- Gpr30-gq complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of GPR30-Gq complex structure in the presence of E2
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xoh
Q-score: 0.503
To Be Published
- Guanine nucleotide-binding protein g(q) subunit alpha-q (41 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from synthetic construct)
- G-protein coupled estrogen receptor 1 (42 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from synthetic construct)
- Gpr30-gq complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Gpr30-g1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of GPR30-Gq complex structure in the presence of fulvestrant
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xoi
Q-score: 0.522
To Be Published
- Gpr30-gq (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha-q (41 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from synthetic construct)
- G-protein coupled estrogen receptor 1 (42 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from synthetic construct)
- Gpr30-gq complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of GPR30-Gq complex structure in the presence of G-1
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8xoj
Q-score: 0.522
To Be Published
- Gpr30-gq (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha-q (41 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from synthetic construct)
- G-protein coupled estrogen receptor 1 (42 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from synthetic construct)
- Gpr30-gq complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)