Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1)
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8hzb
Q-score: 0.491
To Be Published
Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-2)
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8hzc
Q-score: 0.544
To Be Published
Formed alpha-synuclein fibrils after incubation with heparin for 3 days (Hep-remod-3)
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 8hzs
Q-score: 0.52
To Be Published
CCA-bound alpha-synuclein fibrils
Resolution: 2.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ynf
Q-score: 0.618
To Be Published
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8f1c
Q-score: 0.54
Chen YT, Hong MR, Zhang XJ, Kostas J, Li Y, Kraus RL, Santarelli VP, Wang D, Gomez-Llorente Y, Brooun A, Strickland C, Soisson SM, Klein DJ, Ginnetti AT, Marino MJ, Stachel SJ, Ishchenko A
PNAS (2023) 120 pp. e2220029120-e2220029120 [ Pubmed: 37812700 DOI: doi:10.1073/pnas.2220029120 ]
- Potassium ion (39 Da, Ligand)
- (9m)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8h-purin-8-one (437 Da, Ligand)
- Potassium voltage-gated channel subfamily c member 1 (62 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Potassium voltage-gated channel (240 kDa, Complex from Homo sapiens)
Voltage-gated potassium channel Kv3.1 apo
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8f1d
Q-score: 0.512
Chen YT, Hong MR, Zhang XJ, Kostas J, Li Y, Kraus RL, Santarelli VP, Wang D, Gomez-Llorente Y, Brooun A, Strickland C, Soisson SM, Klein DJ, Ginnetti AT, Marino MJ, Stachel SJ, Ishchenko A
PNAS (2023) 120 pp. e2220029120-e2220029120 [ Pubmed: 37812700 DOI: doi:10.1073/pnas.2220029120 ]
- Potassium ion (39 Da, Ligand)
- Potassium voltage-gated channel (240 kDa, Complex from Homo sapiens)
- Potassium voltage-gated channel subfamily c member 1 (62 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cholesterol (386 Da, Ligand)
GTPgammaS Tube decorated with kinesin
Resolution: 6.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ysq
Q-score: 0.108
Zhou J, Wang A, Song Y, Liu N, Wang J, Li Y, Liang X, Li G, Chu H, Wang HW
Nat Commun (2023) 14 pp. 5980-5980 [ Pubmed: 37749104 DOI: doi:10.1038/s41467-023-41615-w ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha chain (49 kDa, Protein from Drosophila melanogaster)
- Tubulin beta-1 chain (50 kDa, Protein from Drosophila melanogaster)
- Gtpgammas-tube decorated with kinesin (440 kDa, Complex from Drosophila melanogaster)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
GTPgammaS MT decorated with kinesin
Resolution: 4.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ysr
Q-score: 0.371
Zhou J, Wang A, Song Y, Liu N, Wang J, Li Y, Liang X, Li G, Chu H, Wang HW
Nat Commun (2023) 14 pp. 5980-5980 [ Pubmed: 37749104 DOI: doi:10.1038/s41467-023-41615-w ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha chain (49 kDa, Protein from Drosophila melanogaster)
- 15-protofilament gtpgammas-mt decorated with kinesin (220 kDa, Complex from Drosophila melanogaster)
- Tubulin beta-1 chain (50 kDa, Protein from Drosophila melanogaster)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
Apo KIF20A[1-565] class-2 in complex with a microtubule
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8f18
Q-score: 0.404
Ranaivoson FM, Crozet V, Benoit MPMH, Abdalla Mohammed Khalid A, Kikuti C, Sirkia H, El Marjou A, Miserey-Lenkei S, Asenjo AB, Sosa H, Schmidt CF, Rosenfeld SS, Houdusse A
Open Biol (2023) 13 pp. 230122-230122 [ Pubmed: 37726093 DOI: doi:10.1098/rsob.230122 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin-like protein kif20a (64 kDa, Protein from Mus musculus)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Kif20a[1-565] apo (Complex from Mus musculus)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Taxol (853 Da, Ligand)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- 15r microtubule (Cellular component from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Kif20a[1-565] apo in complex with a microtubule - class 2 (Complex)
Apo KIF20A[1-565] class-1 in complex with a microtubule
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8f1a
Q-score: 0.463
Ranaivoson FM, Crozet V, Benoit MPMH, Abdalla Mohammed Khalid A, Kikuti C, Sirkia H, El Marjou A, Miserey-Lenkei S, Asenjo AB, Sosa H, Schmidt CF, Rosenfeld SS, Houdusse A
Open Biol (2023) 13 pp. 230122-230122 [ Pubmed: 37726093 DOI: doi:10.1098/rsob.230122 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin-like protein kif20a (64 kDa, Protein from Mus musculus)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Kif20a[1-565] apo (Complex from Mus musculus)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Taxol (853 Da, Ligand)
- Kif20a[1-565] apo in complex with a microtubule (Complex)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- 15r microtubule (Cellular component from Sus scrofa)
- Magnesium ion (24 Da, Ligand)